ELK Biotechnology YB1 (phospho-Ser102) rabbit pAb
YB1 (phospho-Ser102) rabbit polyclonal antibody는 인산화된 YB1 단백질 검출용으로 제작된 항체입니다. WB 분석에 적합하며, 사람 및 생쥐 시료에 반응합니다. 고순도 IgG 형태로 제공되며, -20°C에서 1년간 안정적으로 보관 가능합니다.
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제품명
YB1 (phospho-Ser102) rabbit pAb
기본 정보
| 항목 | 내용 |
|---|---|
| Product name | YB1 (phospho-Ser102) rabbit pAb |
| Alternative Names | Tryptase alpha/beta-1 (Tryptase-1) (EC 3.4.21.59) (Tryptase I) (Tryptase alpha-1) |
| Applications | WB |
| Recommended Dilutions | WB 1:1000–2000 |
| Immunogen | Synthesized phospho peptide around human YB1 (Ser102) |
| Species Reactivity | Human; Mouse |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 30 kD |
| GeneID (Human) | 7177 |
| Human Swiss-Prot No | Q15661 |
| Cellular Localization | Secreted. Released from the secretory granules upon mast cell activation. |
| Storage | -20°C / 1 year |
Background
Tryptases comprise a family of trypsin-like serine proteases belonging to the peptidase family S1. These enzymes are active only as heparin-stabilized tetramers and are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3 and share distinct features such as highly conserved 3' UTRs and tandem repeat sequences that may regulate mRNA stability. These genes contain an intron immediately upstream of the initiator Met codon, separating transcription initiation from the protein coding sequence — a characteristic feature of tryptases. The alleles of this gene exhibit significant sequence variation, previously thought to represent two separate genes.
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