ELK Biotechnology PLIN3 rabbit pAb
PLIN3 단백질을 인식하는 토끼 폴리클로날 항체로, WB 및 ELISA에 적합합니다. 인체 유래 합성 펩타이드로 면역화되었으며, -20°C에서 1년 보관 가능합니다. 인간, 마우스, 랫트 시료에 반응하며, 47kD 밴드를 검출합니다.
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제품명
PLIN3 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 47 kD |
| Gene ID (Human) | 10226 |
| Human Swiss-Prot No | O60664 |
| Species Reactivity | Human; Rat; Mouse |
| Cellular Localization | Lipid droplet; Endosome membrane; Peripheral membrane protein (cytoplasmic side); Cytoplasm; Membrane-associated on endosomes (PubMed:15545278). Detected in the envelope and core of lipid bodies and in lipid sails (PubMed:15545278). |
Background
Mannose 6-phosphate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs, and is required for endosome-to-Golgi transport. This protein also binds directly to the GTPase RAB9 (RAB9A), a member of the RAS oncogene family. The interaction with RAB9 increases the affinity of this protein for its cargo. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Aug 2009]
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