ELK Biotechnology OGG1 rabbit pAb

ELK Biotechnology OGG1 rabbit pAb

제품 개요

OGG1 rabbit pAb는 인간 OGG1 단백질의 특정 펩타이드 서열을 면역원으로 제작된 토끼 폴리클로날 항체입니다. 산화적 DNA 손상 복구 과정 연구에 활용되며, Western blot(WB) 및 ELISA에 적합합니다.

제품 사양

Background

This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct resulting from reactive oxygen exposure. The enzyme exhibits lyase activity for chain cleavage. Alternative splicing of the C-terminal region produces two major groups of splice variants: type 1 (ending with exon 7) and type 2 (ending with exon 8). All variants share the N-terminal region containing a mitochondrial targeting signal essential for mitochondrial localization. Multiple splice variants have been described, though not all full-length forms are confirmed.
[Provided by RefSeq, Aug 2008]