ELK Biotechnology LDHB rabbit pAb
LDHB 단백질을 인식하는 토끼 다클론 항체로, WB 및 ELISA에 적합합니다. 인간, 랫트, 마우스에 반응하며 세포질 및 미토콘드리아 내막에 위치한 단백질 검출에 사용됩니다. 고순도 IgG, 1 mg/ml 농도, -20°C에서 1년 보관 가능합니다.
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제품명
LDHB rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB, ELISA |
| Recommended Dilutions | WB: 1:500–2000 ELISA: 1:5000–20000 |
| Immunogen | Synthesized peptide derived from part region of human protein (AA range 65–105) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 36 kDa |
| Gene ID (Human) | 3945 |
| Human Swiss-Prot No. | P07195 |
| Cellular Localization | Cytoplasm, Mitochondrion inner membrane; Peripheral membrane protein |
| Species Reactivity | Human, Rat, Mouse |
Background
This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5, and 13. [provided by RefSeq, Feb 2016]
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