ELK Biotechnology RBM10 rabbit pAb

제품명

RBM10 rabbit pAb

공급업체

ELK Biotechnology

제품 설명

RBM10 단백질을 표적하는 토끼 폴리클로날 항체로, 인간, 생쥐, 랫트 시료에서 사용 가능합니다. RNA 결합 모티프를 가진 핵 단백질 연구에 적합하며, 대체 스플라이싱 조절 및 TARP 증후군 관련 연구에 활용됩니다.

제품 스펙

세포 내 위치

Nucleus. In the extranucleolar nucleoplasm constitutes hundreds of nuclear domains, which dynamically change their structures in a reversible manner. Upon globally reducing RNA polymerase II transcription, the nuclear bodies enlarge and decrease in number. They occur closely adjacent to nuclear speckles or IGCs (interchromatin granule clusters) but coincide with TIDRs (transcription-inactivation-dependent RNA domains).

배경 정보

This gene encodes a nuclear protein that belongs to a family of proteins that contain an RNA-binding motif. The encoded protein associates with hnRNP proteins and may be involved in regulating alternative splicing. Defects in this gene are the cause of the X-linked recessive disorder, TARP syndrome. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2011]