ELK Biotechnology GLI2 rabbit pAb
GLI2 rabbit polyclonal antibody for WB and ELISA applications. Recognizes human and mouse GLI2 protein. Derived from synthesized human peptide. Stable at -20°C for 1 year. Suitable for nuclear and cytoplasmic localization studies.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology GLI2 rabbit pAb
제품명
GLI2 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB; ELISA |
| Recommended Dilutions | WB: 1:500–2000, ELISA: 1:5000–20000 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Species Reactivity | Human; Mouse |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 174 kD |
| GeneID (Human) | 2736 |
| Human Swiss-Prot No | P10070 |
| Storage | -20°C / 1 year |
| Sample Source | Rabbit |
세포 내 위치
Nucleus, Cytoplasm, Cell projection (cilium).
STK36 promotes translocation to the nucleus. In keratinocytes, it is sequestered in the cytoplasm by SUFU.
In the absence of SUFU, it translocates to the nucleus.
Isoform 1: Nucleus; Isoform 2: Nucleus.
배경 정보
This gene encodes a protein belonging to the C2H2-type zinc finger protein subclass of the Gli family.
Members of this subclass act as transcription factors binding DNA through zinc finger motifs with conserved H-C links.
Gli family zinc finger proteins mediate Sonic hedgehog (Shh) signaling and function as potent oncogenes in embryonal carcinoma cells.
The protein localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression.
It plays roles in embryogenesis and is associated with phenotypes such as Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B.
(Provided by RefSeq, Jul 2008)
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.