ELK Biotechnology HLAE rabbit pAb
HLAE rabbit pAb는 인간 HLA-E 단백질을 인식하는 폴리클로날 항체로, WB 및 ELISA에 적합합니다. 합성 펩타이드 면역원으로 제작되었으며, -20°C에서 1년 보관 가능합니다. 세포막 및 골지체 막 단백질 검출에 유용합니다.
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제품명
HLAE rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB, ELISA |
| Recommended Dilutions | WB: 1:500–1:2000 ELISA: 1:5000–1:20000 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 39 kDa |
| GeneID (Human) | 3133 |
| Human Swiss-Prot No. | P13747 |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein; Golgi apparatus membrane; Secreted (Soluble HLA class I histocompatibility antigen, alpha chain E) |
| Species Reactivity | Human |
Background
HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. (provided by RefSeq, Jul 2008)
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