ELK Biotechnology GSTM2 rabbit pAb

제품명

GSTM2 rabbit pAb

제품 개요

ELK Biotechnology에서 제공하는 GSTM2 rabbit polyclonal antibody는 인간, 랫, 마우스 시료에서 GSTM2 단백질을 검출하기 위한 항체로, WB 및 ELISA 실험에 적합합니다.

제품 사양

Background

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. Eight distinct classes of soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta, and zeta.
This gene encodes a glutathione S-transferase belonging to the mu class, which functions in detoxification of electrophilic compounds — including carcinogens, therapeutic drugs, environmental toxins, and oxidative stress products — by conjugation with glutathione.
The genes encoding the mu class enzymes are organized in a gene cluster on chromosome 1p13.3 and are highly polymorphic. These genetic variations can influence individual susceptibility to carcinogens and toxins, as well as affect drug toxicity and efficacy.
[provided by RefSeq, Jul 2008]