ELK Biotechnology ELAV1 rabbit pAb
상품 옵션 정보 | ||||||
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카탈로그 번호 | 설명 | 상태 | 단위 | 가격 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
ES11889-100UL | ELK Biotechnology ES11889-100UL ELAV1 rabbit pAb, 100UL pk | 재고문의 | pk | 469,000원 | 515,900원 | |
ES11889-50UL | ELK Biotechnology ES11889-50UL ELAV1 rabbit pAb, 50UL pk | 재고문의 | pk | 320,000원 | 352,000원 |
다른 상품 둘러보기
Product name: | ELAV1 rabbit pAb |
Applications: | WB;ELISA |
Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
Immunogen: | Synthesized peptide derived from part region of human protein |
Storage: | Rabbit |
Storage: | -20°C/1 year |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 1 mg/ml |
Observed Band: | 35kD |
GeneID(Human): | 1994 |
Human Swiss-Prot No: | Q15717 |
Cellular localization: | Cytoplasm . Nucleus . Cytoplasm, Stress granule . Cytoplasm, P-body . Translocates into the cytoplasm following phosphorylation by MAPKAPK2 (PubMed:14517288). Likewise, phosphorylation by PRKCD promotes translocation from the nucleus into the cytoplasm, where it is associated with free and cytoskeleton-bound polysomes (PubMed:18285462).Localizes to the stress granules in the presence of PLEKHN1 (By similarity). . |
Background: | ELAV like RNA binding protein 1(ELAVL1) Homo sapiens The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3` untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012], |
Species Reactivity: | Human;Mouse |
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