Thermo Fisher Scientific ZBTB8A Polyclonal Antibody
인간 ZBTB8A 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:200–1:500 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS(glycerol 포함) 용액 형태로 제공. 연구용으로만 사용 가능.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ZBTB8A. Recombinant protein control fragment (Product # RP-103763) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2649786 |
Product Specific Information
Immunogen sequence:
SQPSEVTHYK SSKREVRTSD SSSHVSQSEE QAQIDAEMDS TPVGYQYGQG SDVTSKSFPD DLPRMRFKCP YC
Highest antigen sequence identity to orthologs:
- Mouse: 61%
- Rat: 67%
Target Information
The ZBTB family of proteins comprises diverse zinc finger proteins that also contain a BTB (BR-C, ttk, and bab) domain.
ZBTB8 (also known as BOZ-F1) is expressed in multiple tissues and is highly expressed in the cytoplasm of the placenta.
While little is known about ZBTB8, other ZBTB proteins such as ZBTB4 bind methylated DNA and repress transcription.
ZBTB7A has been implicated as a proto-oncogene whose overexpression contributes to malignancy in breast cancer, suggesting that ZBTB8 may act as a transcriptional repressor or be involved in tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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