Thermo Fisher Scientific ZBTB8A Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ZBTB8A. Recombinant protein control fragment (Product #RP-103763). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ZBTB8A,uniProtId:Q96BR9-1,ncbiNodeId:9606,antigenRange:216-287,antigenLength:441,antigenImageFileName:PA5-56850_ZBTB8A_Q96BR9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-56850_ZBTB8A_Q96BR9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2649786

Product Specific Information

Immunogen sequence: SQPSEVTHYK SSKREVRTSD SSSHVSQSEE QAQIDAEMDS TPVGYQYGQG SDVTSKSFPD DLPRMRFKCP YC

Highest antigen sequence identity to the following orthologs: Mouse - 61%, Rat - 67%.

Target Information

The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB8, also known as BOZ-F1, is present in multiple tissues, and is highly expressed in the cytoplasm of the placenta. While little is known about ZBTB8, other ZBTB proteins, such as ZBTB4 bind methylated DNA and repress transcription. Another ZBTB proteins, ZBTB7A, has been implicated as a proto-oncogene whose overexpression contributes to malignancy in breast cancer, suggesting that ZBTB8 may act as a transcriptional repressor or be involved in tumorigenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.