Thermo Fisher Scientific EDA Monoclonal Antibody (8A5)
EDA 단백질을 인식하는 Mouse IgG1 단일클론 항체로, ELISA에 적합. 인간 종에 반응하며 PBS(pH 7.4) 용액 형태로 제공. 보존제 무첨가, -20°C에서 보관. 연구용으로 ectodermal dysplasia 관련 연구에 활용 가능.
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Applications
- ELISA (ELISA)
Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 8A5 |
| Immunogen | EDA (NP_001390.1, 245 a.a. approximately 391 a.a) partial recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
ENQPAVVHLQ GQGSAIQVKN DLSGGVLNDW SRITMNPKVF KLHPRSGELE VLVDGTYFIY SQVEVYYINF TDFASYEVVV DEKPFLQCTR SIETGKTNYN TCYTAGVCLL KARQKIAVKM VHADISINMS KHTTFFGAIR LGEAPAS
Target Information
EDA is a type II membrane protein that can be cleaved by furin to produce a secreted form. This protein, belonging to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs.
Defects in the EDA gene cause ectodermal dysplasia, anhidrotic, also known as X-linked hypohidrotic ectodermal dysplasia.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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