Thermo Fisher Scientific DAP3 Monoclonal Antibody (OTI1A12)
DAP3 단백질을 인식하는 마우스 모노클로날 항체로 Western blot과 IHC(P)에서 사용 가능. Human 시료에 반응하며, 1 mg/mL 농도의 액상 형태로 제공. Affinity Chromatography로 정제되었으며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 161–398 of DAP3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724190 |
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and assist in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit, with approximately 75% protein to rRNA composition, in contrast to prokaryotic ribosomes. Unlike prokaryotic ribosomes, mammalian mitoribosomes lack a 5S rRNA. The proteins comprising the mitoribosome vary significantly among species, making sequence-based identification difficult. The DAP3 gene encodes a 28S subunit protein involved in apoptotic pathways triggered by TNF-alpha, Fas ligand, and gamma interferon. This protein may bind ATP/GTP and function as a partner of the mitoribosomal protein S27. Splice variants in the 5′ UTR exist but encode the same protein. Pseudogenes are located on chromosomes 1q and 2q.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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