Thermo Fisher Scientific Mouse SCF, AOF Recombinant Protein
Recombinant mouse stem cell factor (SCF) protein expressed in E. coli. Animal origin-free and lyophilized form for research use. Supports studies on c-Kit signaling, mast cell survival, and inflammatory pathways. Stable at -20°C and shipped on wet ice.
- 카탈로그번호
- RP877xx (5개 옵션)
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
5개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Mouse SCF, AOF Recombinant Protein
Thermo Fisher Scientific Mouse SCF, AOF Recombinant Protein
Applications
- Assay-dependent
- Suitable for research on c-Kit signaling and inflammatory responses
Product Specifications
| 항목 | 내용 |
|---|---|
| Expression System | E. coli |
| Class | Recombinant |
| Type | Protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Animal Origin Free (AOF)
- Reconstitute with sterile water to 0.1 mg/mL concentration
Target Information
Stem cell factor (SCF) is the ligand of the c-Kit oncogene and is expressed by various structural and inflammatory cells in the airways. Binding of SCF to the c-Kit receptor induces receptor homodimerization and activates signaling pathways such as PI-3, PLC-gamma, Jak/STAT, and MAP kinase. SCF promotes mast cell survival and triggers histamine and cytokine release. Inhibition of the SCF/c-Kit pathway reduces histamine levels, mast cell and eosinophil infiltration, IL-4 production, and airway hyperresponsiveness, suggesting its potential as a therapeutic target in inflammatory diseases such as asthma. At least two isoforms of SCF are known to exist.
Usage Notes
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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