Thermo Fisher Scientific Ribophorin I Polyclonal Antibody
Ribophorin I 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 적합합니다. 인간 시료 반응성이 있으며, 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol buffer에 보관되며 연구용으로 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human RPN1. Recombinant protein control fragment (Product #RP-104924) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662372 |
Product Specific Information
Immunogen sequence:
DVKRTVDLSSH LAKVTAEVVL AHLGGGSTSR ATSFLLALEP ELEARLAHLG VQVKGEDEEE NNLEVRETKI KGKSGRFFTV KLPVALDPGA KISVIVETVY THVLHPYPTQ ITQSEKQFVV FEGNHYFYSP YPTKTQ
- Highest antigen sequence identity to the following orthologs: mouse 93%, rat 93%.
Target Information
Ribophorins 1 and 2 are abundant and highly conserved glycoproteins located in the endoplasmic reticulum, involved in ribosome binding. Mammalian oligosaccharyltransferase activity is associated with a complex composed of RPN1, RPN2, and an oligosaccharyltransferase protein.
RPN1 is a component of the proteasome base. The ubiquitin-like (UBL) domain of recombinant Rad23 interacts with proteasomes through the leucine-rich repeat domain of RPN1.
The RPN1 gene maps to chromosome 3, and the RPN2 gene maps to chromosome 20 by in situ hybridization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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