Thermo Fisher Scientific TSC22D1 Monoclonal Antibody (OTI3B7), TrueMAB
Human TSC22D1 단백질을 인식하는 Mouse monoclonal antibody. Western blot 및 IHC(Paraffin) 검증 완료. 고순도 Affinity chromatography 정제. PBS/BSA/glycerol buffer, -20°C 보관. 세포 성장 및 분화 연구용.
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Thermo Fisher Scientific TSC22D1 Monoclonal Antibody (OTI3B7), TrueMAB
Applications and Tested Dilution
- Western Blot (WB): 1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3B7 |
| Immunogen | Full length human recombinant protein of TSC22D1 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
TSC22 domain family protein (TSC22D1) is a transcription factor belonging to the early response gene family. It acts as a transcriptional repressor on the C-type natriuretic peptide (CNP) promoter and is part of the TSC-22/Dip/Bun family. The protein localizes to both cytoplasm and nucleus, regulating cell growth, differentiation, and apoptosis. It modulates Smad3 and Smad4 transcriptional activity, and is expressed broadly in fetal and adult tissues, including aortic endothelial cells. Induced by cytokines such as TGFB, TSC22D1 may serve as a potential therapeutic target in leukemia and prostate cancer research.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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