Thermo Fisher Scientific PRR7 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human PRR7. Recombinant protein control fragment (Product #RP-90213). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PRR7,uniProtId:Q8TB68-1,ncbiNodeId:9606,antigenRange:147-266,antigenLength:274,antigenImageFileName:PA5-61266_PRR7_Q8TB68-1_Rabbit.svg,antigenImageFileNamePDP:PA5-61266_PRR7_Q8TB68-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2646001

Product Specific Information

Immunogen sequence: MSKPPCYEEA VLMAEPPPPY SEVLTDTRGL YRKIVTPFLS RRDSAEKQEQ PPPSYKPLFL DRGYTSALHL PSAPRPAPPC PALCLQADRG RRVFPSWTDS ELSSREPLEH GAWRLPVSIP

Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.

Target Information

PRR7/TRAP3 (proline-rich 7, transmembrane adaptor protein 3) is a 28 kDa transmembrane adaptor protein ubiquitously expressed at low level (most in brain). Its amino acid sequence is extremely conserved among mammalian and other species. PRR7/TRAP3 contains potential palmitoylation motif and is found in lipid rafts. It is a part of the complex postsynaptic density fraction in neurons and associates with PSD-95, NMDA receptor and probably other proteins. The intracellular domain of PRR7/TRAP3 contains several tyrosines, a proline-rich sequence, and a C-terminal PDZ-binding motif. So far nothing is known about function of this protein. It may be involved in regulation of some receptor signaling and in formation of neurologic and immunologic synapse.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.