Thermo Fisher Scientific COPB2 Polyclonal Antibody
Thermo Fisher Scientific의 COPB2 폴리클로날 항체는 인간 및 생쥐 시료에서 COPB2 단백질 검출에 적합합니다. Rabbit IgG 기반으로 제작되었으며, Western blot에 최적화되어 있습니다. 항원 친화 크로마토그래피로 정제되었으며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications
- Western Blot (WB): 1:1,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide between amino acids 814–843 from the C-terminal region of human COPB2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2634569 |
Target Information
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, mediating biosynthetic protein transport from the ER through the Golgi to the trans-Golgi network. The coatomer complex is required for budding from Golgi membranes and is essential for retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, recruitment occurs via ADP-ribosylation factors (ARFs), small GTP-binding proteins that also influence Golgi structural integrity and the processing, activity, and recycling of LDL receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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