Thermo Fisher Scientific Fibrinogen (gamma) Polyclonal Antibody
Thermo Fisher Scientific의 Fibrinogen (gamma) Polyclonal Antibody는 인간 및 마우스 시료에서 Fibrinogen γ 단백질 검출에 적합합니다. WB 및 IHC(P) 응용에 사용 가능하며, 항원 친화 크로마토그래피로 정제된 고순도 제품입니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the N-terminal portion of Fibrinogen gamma protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Mouse liver
- Cellular location: Cytoplasmic, Peripheral membrane
Target Information
The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein composed of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin, the most abundant component of blood clots. Various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and act as mitogens for several cell types. Mutations in this gene can lead to disorders such as dysfibrinogenemia, hypofibrinogenemia, and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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