Thermo Fisher Scientific LDHA Monoclonal Antibody (OTI2B11), Biotin, TrueMAB
인간 LDHA 단백질을 인식하는 Biotin 결합 단클론 항체로 ELISA 및 Luminex 분석에 적합. 고순도 Affinity chromatography 정제. -20°C 보관, 동결/해동 반복 금지. 연구용으로만 사용.
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Thermo Fisher Scientific LDHA Monoclonal Antibody (OTI2B11), Biotin, TrueMAB
Applications and Tested Dilution
- ELISA (ELISA): 1:250–1:1,000
- Luminex (LUM): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B11 |
| Immunogen | Protein expressed in 293T cell transfected with human LDHA expression vector |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 10 mg/mL BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
Lactate dehydrogenase (LDH) is the enzyme in the glycolytic pathway that converts pyruvate to lactate with concomitant interconversion of NADH and NAD+.
In mammals, the enzyme is encoded by three genes: LDHA (muscle form), LDHB (heart form), and LDHC (testis form).
The three human LDHs share 84–89% sequence similarity and 69–75% amino acid identity.
There are five LDH isoenzymes based on the proportion of M and H chains in the tetrameric structure.
LDHA is hypoxia-inducible and regulated by HIF1a transcriptional activity.
LDHB is upregulated in many cancers.
Mutations in the LDHA gene can cause Glycogen Storage Disease 11 (GSD11).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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