Thermo Fisher Scientific C1orf180 Polyclonal Antibody
Human C1orf180 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능. 고순도 Protein A 정제, 안정적인 액상 형태, -20°C 보관. 연구용으로 적합한 고신뢰 항체.
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Thermo Fisher Scientific C1orf180 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human C1orf180 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
AIDA, also known as C1orf80, is a 306 amino acid protein that belongs to the axin interactor family. It is expressed in various tissues, including skeletal muscle and heart. AIDA functions as a ventralizing factor during embryogenesis by disrupting Axin homodimerization and inhibiting Axin-mediated JNK activation. Axin, a scaffold protein, plays a key role in JNK signaling and the canonical Wnt pathway, both essential for embryonic dorsoventral patterning. Disruption of Axin by AIDA negatively regulates JNK and Wnt signaling, affecting embryonic development. Three isoforms of AIDA exist due to alternative splicing events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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