Thermo Fisher Scientific PD-1 Monoclonal Antibody (J43)
Mouse PD-1 단백질을 인식하는 Armenian hamster 유래 단클론 항체로, Flow Cytometry(FACS)에 사용 가능. 비접합형이며 다양한 형광 접합 옵션 제공. 단백질 G 정제, PBS 버퍼 및 sodium azide 포함. 단기 4°C, 장기 -20°C 보관.
- 카탈로그번호
- PA535008
- 판매단위
- pk
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 2.0 µg/1x10^6 cells
- View 7 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Armenian hamster / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | J43 |
| Immunogen | PD-1 cDNA transfectant |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2552335 |
Additional Formats
Product Specific Information
PA5-35008 targets CD279/PD1 in FACS applications and shows reactivity with Mouse samples.
The PA5-35008 immunogen is PD-1 cDNA transfectant.
Target Information
Cell-mediated immune responses are initiated by T lymphocytes stimulated by peptides bound to MHC molecules on antigen-presenting cells (APC).
Activated T cells express PD-1 (also known as PDCD-1), which mediates inhibitory signals from APCs. PD-1 binds to ligands PDL-1 and PDL-2, leading to inhibition of immune activation in the absence of danger signals such as LPS.
PD-1 deficient mice exhibit hyperactivated immune systems and autoimmune diseases. Despite its predicted molecular weight, PD-1 often migrates at a higher molecular weight in SDS-PAGE.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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