Thermo Fisher Scientific DNASE2B Polyclonal Antibody
DNASE2B 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot에 적합합니다. 인간 및 랫트 시료에 반응하며, 고순도 친화 크로마토그래피로 정제되었습니다. PBS/glycerol 완충액에 보관되며, 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5100482
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DNASE2B (Accession Q8WZ79), corresponding to amino acid residues Y302–G352 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2849992 |
Product Specific Information
This antibody detects endogenous levels of total DNASE2B.
Target Information
The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II, an endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II, which is ubiquitously expressed, DNASE2B expression is restricted to the salivary gland and lungs. The gene is localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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