Thermo Fisher Scientific SOCS3 Monoclonal Antibody (OTI11C5), TrueMAB
인간 SOCS3 단백질을 인식하는 마우스 단클론 항체로, Western blot, ICC/IF, Flow Cytometry에 사용 가능. 고순도의 액상 형태로 제공되며, -20°C에서 보관. 사이토카인 신호 억제 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI11C5 |
| Immunogen | Full length human recombinant protein of human SOCS3 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cytokine receptor signaling is negatively regulated by the SOCS (Suppressor of Cytokine Signaling) family, which includes SOCS-1 to SOCS-7 and CIS. These proteins contain an N-terminal region, a central SH2 domain, and a C-terminal SOCS box motif. SOCS proteins function as part of a negative feedback loop that regulates cytokine signal transduction via STAT-induced transcriptional mechanisms. Expression of SOCS genes is rapidly induced by cytokines, and each member inhibits signaling through distinct mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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