
Thermo Fisher Scientific PPP2R1B Monoclonal Antibody (OTI8C5), TrueMAB
PPP2R1B 단백질을 인식하는 Mouse monoclonal antibody로 Western blot에 최적화되어 있습니다. Human 시료에 반응하며, 고순도의 affinity chromatography로 정제되었습니다. -20°C에서 보관하며, 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8C5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 19–601 of human PPP2R1B produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues regulate a broad range of cellular functions such as division, homeostasis, and apoptosis. Protein phosphatases are key enzymes in this process. The protein phosphatase (PP) holoenzyme is typically a trimeric complex consisting of a regulatory subunit, a variable subunit, and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified: PP1, PP2A, PP2B (calcineurin), and PP2C. An additional catalytic subunit, PPX (also known as PP4), represents a potential new PP family. The PP2A family includes subfamily members PP2A alpha and PP2A beta, which associate with various regulatory subunits such as PP2A-A alpha and -A beta, PP2A-B alpha and -B beta, PP2A-C alpha and -C beta, and PP2A-B56 alpha and -B56 beta.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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