Thermo Fisher Scientific PARN Monoclonal Antibody (OTI4E12)
PARN 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot과 IHC(파라핀 절편)에 적합합니다. 인간 단백질(aa 1–266)을 면역원으로 제작되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4E12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–266 of PARN produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724940 |
Target Information
The protein encoded by this gene is a 3'-exoribonuclease with similarity to the RNase D family of 3'-exonucleases. It preferentially degrades poly(A) tails of mRNAs, initiating the decay of eukaryotic mRNAs. This protein participates in silencing of maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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