Thermo Fisher Scientific TFF2 Monoclonal Antibody (1-2#)
Thermo Fisher Scientific의 TFF2 단클론 항체(1-2#)는 쥐 단백질에 반응하며 Western blot, IHC, ICC/IF에 사용 가능합니다. 재조합 TFF2 단백질(aa 27-129)을 면역원으로 제작되었으며, 고순도 Protein A/G 정제 및 PBS+50% glycerol 저장 형태로 제공됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.5–2 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 5–20 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 5–20 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host/Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1-2# |
| Immunogen | Recombinant protein Trefoil Factor 2 (amino acids 27–129) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899165 |
Target Information
Trefoil peptides are protease-resistant molecules secreted throughout the gut that play a role in mucosal healing and protection of gastrointestinal epithelia. These peptides contain three intrachain disulfide bonds forming the trefoil motif (P-domain).
SP (spasmolytic polypeptide), also designated Trefoil Factor 2 (TFF2) precursor, inhibits gastrointestinal motility and gastric acid secretion. It may also stabilize glycoproteins in the mucus gel through carbohydrate side chain interactions.
Downregulation of SP expression is associated with primary gastric cancer and may contribute to early stages of gastric carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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