Thermo Fisher Scientific PLA2G4A/cPLA2 Polyclonal Antibody
PLA2G4A/cPLA2에 특이적인 Rabbit Polyclonal Antibody로, Western blot 및 Immunoprecipitation에 사용 가능. Human 반응성, 항원 친화 크로마토그래피로 정제. 액상 형태, 1 mg/mL 농도, 4°C 보관. 연구용으로만 사용.
- 카탈로그번호
- A305204Ax (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PLA2G4A/cPLA2 Polyclonal Antibody
Applications
- Western Blot (WB): Assay-dependent
- Immunoprecipitation (IP): 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 425 to 475 of Human Cytosolic phospholipase A2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan
Target Information
This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid, which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca²⁺ levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: A305-204A_PLA2G4A_P47712-1_Rabbit_PDP.jpeg, A305-204A_PLA2G4A_P47712-1_Rabbit.svg)
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