Thermo Fisher Scientific Human SOD1 Recombinant Protein, PeproTech

Applications

Tested Dilution

Publications

Functional Assay (Functional)

Assay-dependent

-

Product Specifications

Species

Human

Expression System

E. coli

Amino acid sequence

MHHHHHHATK AVCVLKGDGP VQGIINFEQK ESNGPVKVWG SIKGLTEGLH GFHVHEFGDN TAGCTSAGPH FNPLSRKHGG PKDEERHVGD LGNVTADKDG VADVSIEDSV ISLSGDHCII GRTLVVHEKA DDLGKGGNEE STKTGNAGSR LACGVIGIAQ

Tag

His-tag

Molecular weight

16.8 kDa

Class

Recombinant

Type

Protein

Purity

≥98% by SDS-PAGE gel and HPLC analyses.

Endotoxin concentration

<1 EU/µg

Activity

Determined by its ability to decrease superoxide concentration when tested using an SOD colorimetric activity kit.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Purification

purified

Contains

no preservative

Storage conditions

-20°C

Shipping conditions

Ambient

Product Specific Information

Recombinant Human SOD is a 16.8 kDa protein containing 160 amino acid residues including an N-terminal His-tag.

This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Target Information

SOD1 (superoxide dismutase) binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.