Thermo Fisher Scientific TDP1 Polyclonal Antibody
TDP1 단백질을 인식하는 염소 유래 폴리클로날 항체로, Western blot에 최적화되어 있습니다. 인간 시료에 반응하며, 0.5 mg/mL 농도의 액상 형태로 제공됩니다. DNA 손상 복구 연구에 활용 가능합니다. -20°C에서 보관하세요.
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Applications
- Western Blot (WB): 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-PNDGTAQRTENHG |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933040 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:8,000.
Target Information
The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA.
It may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in the repair of free-radical mediated DNA double-strand breaks.
This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains.
Mutations in this gene are associated with spinocerebellar ataxia with axonal neuropathy (SCAN1).
Several transcript variants exist, but two major variants encode the same isoform.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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