
Thermo Fisher Scientific FMNL1 Polyclonal Antibody
FMNL1 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 IHC(파라핀 절편)에서 사용 가능. Human에 반응하며 Mouse, Rat에도 예측 반응. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성 제공.
- 카탈로그번호
- PA522228
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 631–903 of FMNL1 (Uniprot ID: O95466) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.39 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_11155834 |
Product Specific Information
- Recommended positive control: Raji
- Predicted reactivity: Mouse (90%), Rat (90%)
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
Formin-like protein 1 (FRL1) 유전자는 형태형성, 세포분열, 세포 극성에 관여하는 formin 관련 단백질을 암호화합니다. Formin 단백질은 모든 진핵생물에서 보존된 단백질군으로, DAD (diaphanous autoregulatory domain), FH2 (formin homology 2), GBD/FH3 (Rho GTPase-binding/formin homology 3) 도메인을 포함합니다. FRL1은 세포질에 위치하며 비장, 림프절, 골수 세포에서 높게 발현됩니다. 세포 운동성 조절, 대식세포 생존, 세포골격 조직화에 관여할 가능성이 있습니다.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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