Thermo Fisher Scientific ATP2A3 Monoclonal Antibody (2H3)
ATP2A3 단백질을 인식하는 Thermo Fisher Scientific의 단일클론 항체로, WB, IHC, ELISA에 적합합니다. Human에 반응하며 Mouse IgG2a, kappa 형식입니다. 고순도 친화 크로마토그래피로 정제되어 연구용으로 안정적인 결과를 제공합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3 µg/mL |
| ELISA | 0.3 ng/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2H3 |
| Immunogen | ATP2A3 (AAH35729, 501 a.a. approximately 620 a.a) partial recombinant protein with GST tag (MW of GST tag alone: 26 KDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
TRPHPTGQGS KMFVKGAPES VIERCSSVRV GSRTAPLTPT SREQILAKIR DWGSGSDTLR CLALATRDAP PRKEDMELDD CSKFVQYETD LTFVGCVGML DPPRPEVAAC ITRCYQAGIR
Target Information
ATP-dependent calcium pumps help maintain low cytoplasmic calcium concentrations. These pumps, located in intracellular organelles, belong to the SERCA (sarcoplasmic/endoplasmic reticulum calcium ATPase) family.
The SERCA2 gene generates tissue-specific isoforms:
- SERCA2a: muscle-specific isoform expressed in type I skeletal, cardiac, and smooth muscle
- SERCA2b: expressed in all cell types
SERCA3 is co-expressed with SERCA2b in platelets, mast cells, lymphoid cells, and epithelial cells, and is known as the non-muscle form of SERCA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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