Thermo Fisher Scientific SF3B4 Polyclonal Antibody
SF3B4 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot, IHC, ICC/IF에 사용 가능. 인간, 생쥐, 랫트 반응성. 고순도 친화 크로마토그래피 정제. PBS/glycerol buffer 형태로 -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SF3B4 (Accession Q15427), corresponding to amino acid residues M1–L32 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851341 |
Product Specific Information
This antibody detects endogenous levels of total SF3B4.
Target Information
The SF3B4 gene encodes one of four subunits of the splicing factor 3B complex. The encoded protein cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence within the prespliceosomal complex A. It is also involved in the assembly of spliceosomal complexes B, C, and E. In addition to RNA-binding activity, this protein interacts directly and specifically with subunit 2 of the splicing factor 3B. The protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with its ability to bind directly to pre-mRNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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