Thermo Fisher Scientific CXCL9 (MIG) Monoclonal Antibody (MIG-2F5.5), PE, eBioscience

Thermo Fisher Scientific CXCL9 (MIG) Monoclonal Antibody (MIG-2F5.5), PE, eBioscience

Applications

• Flow Cytometry (Intracellular staining)

Tested Dilution

• ≤ 0.25 µg/test

Publications

• View 2 publications

Product Specifications

Product Specific Information

The monoclonal antibody MIG-2F5.5 reacts with mouse monokine induced by IFN gamma (MIG, MIG-1, CXCL9). This 14.4 kDa inflammatory chemokine is specifically induced by IFN gamma, but not by LPS or IFN alpha. MIG secretion, mainly by macrophages, results in chemotaxis of activated T cells via the CXCR3 receptor. MIG is involved in autoimmune disease, cancer, and inflammation research.

Applications Reported:
This antibody is suitable for intracellular staining followed by flow cytometric analysis.

Applications Tested:
Tested by intracellular staining of IFN-γ stimulated thioglycolate-elicited peritoneal exudate cells and RAW 264.7 cells. Use ≤ 0.25 µg per test (100 µL final volume). Optimal titration recommended.

Excitation / Emission / Laser:

• Excitation: 488–561 nm
• Emission: 578 nm
• Laser: Blue, Green, Yellow-Green

Filtration:
0.2 µm post-manufacturing filtered.

Target Information

MIG (CXCL9) is a T-cell chemoattractant induced by gamma interferon, belonging to the CXC chemokine family. Mapped to 4q21, it influences T-cell activation, angiogenesis, and HIV infection. Unlike most CXC chemokines that attract neutrophils, MIG and INP10 are chemotactic for lymphocytes and inactive in neutrophils.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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