Thermo Fisher Scientific DC-SIGN Polyclonal Antibody
Rabbit polyclonal antibody targeting DC-SIGN (CD209). Validated for WB, IHC(P), and ICC/IF. Recognizes mouse DC-SIGN protein (aa 115–238). Supplied as liquid, 1 mg/mL in PBS with 50% glycerol. For research use only.
- 카탈로그번호
- PA5119030
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific DC-SIGN Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:50–400 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–100 |
| Immunocytochemistry (ICC/IF) | 1:50–500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein Cluster Of Differentiation 209 (amino acids 115–238 of target protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903530 |
Target Information
This gene encodes a transmembrane receptor commonly referred to as DC-SIGN, expressed on the surface of dendritic cells and macrophages. The encoded protein participates in the innate immune system and recognizes a wide range of pathogens, including parasites and viruses.
The protein structure includes:
- N-terminal transmembrane domain
- Tandem-repeat neck domain
- C-type lectin carbohydrate recognition domain
The extracellular region functions as both a pathogen recognition receptor and a cell adhesion receptor, binding carbohydrate ligands on microbial and host cell surfaces. The neck region enables homo-oligomerization, allowing high-avidity binding to multivalent ligands.
Variations in the neck domain’s amino acid repeats can affect ligand-binding ability. DC-SIGN is closely related to L-SIGN (GeneID 10332) but differs in binding properties and tissue distribution.
Alternative splicing generates multiple variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.