Thermo Fisher Scientific Desmoglein 4 Polyclonal Antibody
Desmoglein 4 단백질을 인식하는 Rabbit Polyclonal 항체. Human, Mouse, Rat 시료에서 Western blot에 사용 가능. Affinity chromatography로 정제된 액상 포맷, 1 mg/mL 농도. PBS/glycerol buffer에 보관하며 -20°C에서 안정적 저장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DSG4 (Accession Q86SJ6), corresponding to amino acid residues S251–D301 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853116 |
Product Specific Information
Antibody detects endogenous levels of total DSG4.
Target Information
Desmoglein proteins are cadherin-type cell adhesion molecules.
Desmoglein 4 (DSG4) shares 41% identity with human desmoglein 1, 37% with desmoglein 2, and 50% with desmoglein 3.
This type I membrane protein is expressed in salivary gland, suprabasal epidermis, hair follicle, testis, prostate, and skin.
In the hair follicle, DSG4 mediates keratinocyte cell adhesion and coordinates the transition from proliferation to differentiation.
The human DSG4 gene is composed of 16 exons spanning approximately 37 kb on chromosome 18q12, located between DSG1 and DSG3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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