Thermo Fisher Scientific GKAP1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human GKAP1. Recombinant protein control fragment (Product #RP-95675). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GKAP1,uniProtId:Q5VSY0-1,ncbiNodeId:9606,antigenRange:276-366,antigenLength:366,antigenImageFileName:PA5-57159_GKAP1_Q5VSY0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-57159_GKAP1_Q5VSY0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2642016

Product Specific Information

Immunogen sequence: ITQWEAKYKE VKARNAQLLK MLQEGEMKDK AEILLQVDES QSIKNELTIQ VTSLHAALEQ ERSKVKVLQA ELAKYQGGRK GKRNSESDQC R

Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.

Target Information

The approximately 142 kDa Tankyrase protein is ubiquitously expressed in mammalian cells and is localized to human telomeres. It has homology to ankyrins and to the catalytic domain of poly (adenosine diphosphate-ribose) polymerase (PARP). Tankyrase binds to TRF1 (telomeric repeat binding factor-1), which negatively regulates the maintenance of telomere length.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.