
Thermo Fisher Scientific BLNK Monoclonal Antibody (OTI4C9)
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Applications
Tested Dilution
Publications
Western Blot (WB)
1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
1:150
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse / IgG2b
Class
Monoclonal
Type
Antibody
Clone
OTI4C9
Immunogen
Human recombinant protein fragment corresponding to amino acids 1-292 of BLNK produced in E.coli if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
BLNK,
uniProtId:
Q8WV28-1,
ncbiNodeId:
9606,
antigenRange:
1-292,
antigenLength:
456,
antigenImageFileName:
MA5-27007_BLNK_Q8WV28-1_House_mouse.svg,
antigenImageFileNamePDP:
MA5-27007_BLNK_Q8WV28-1_House_mouse_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2723989
Target Information
B cell linker protein (Blnk) is a protein encoded by the Blnk gene located on chromosome 10 in humans. It is also known as SLP 65 (Src homology 2 domain-containing leukocyte protein of 65 kDa). It derives its name from being an adaptor protein in the B cell receptor signaling cascade with several supporting studies showing improper development of B cells in the absence of Blnk. Blnk undergoes tyrosine phosphorylation by Syk, a B cell receptor activated kinase, which provides a platform for interaction of signaling intermediaries such as the Vav GEF and Grb2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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