Thermo Fisher Scientific FAM149B1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human FAM149B1, validated for IHC and ICC/IF applications. Specific to cilium-associated protein involved in Joubert syndrome. Supplied as liquid, unconjugated form, 0.1 mg/mL concentration, stored at 4°C or -20°C.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
- Publications: [References not provided]
Immunocytochemistry (ICC/IF)
- Tested Concentration: 0.25–2 µg/mL
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FAM149B1 (control fragment: Product #RP-97086) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641272 |
Product Specific Information
Immunogen sequence:
DDKLLMRPGS STILSTRNWP NRAVEFSTSS LSYTVQSTRR RNPPPRTLHP ISTSHSCAET PRSVEEILRG ARVPVAPDSL SSPSP
Antigen sequence identity:
- Mouse: 81%
- Rat: 79%
Target Information
FAM149B1 is involved in cilium assembly and protein localization to the cilium. It is predicted to be located in the cilium and implicated in Joubert syndrome.
This gene encodes a protein associated with Joubert Syndrome 36 and Orofaciodigital Syndrome VI.
An important paralog of FAM149B1 is FAM149A.
It contributes to the localization of proteins to the cilium and indirectly regulates SHH/smoothened signaling for proper development.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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