Thermo Fisher Scientific FAM149B1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human FAM149B1. Recombinant protein control fragment (Product #RP-97086). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FAM149B1,uniProtId:Q96BN6-1,ncbiNodeId:9606,antigenRange:379-463,antigenLength:582,antigenImageFileName:PA5-58953_FAM149B1_Q96BN6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-58953_FAM149B1_Q96BN6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2641272

Product Specific Information

Immunogen sequence: DDKLLMRPGS STILSTRNWP NRAVEFSTSS LSYTVQSTRR RNPPPRTLHP ISTSHSCAET PRSVEEILRG ARVPVAPDSL SSPSP

Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 79%.

Target Information

Involved in cilium assembly and protein localization to cilium. Predicted to be located in cilium. Implicated in Joubert syndrome. FAM149B1 (Family With Sequence Similarity 149 Member B1) is a Protein Coding gene. Diseases associated with FAM149B1 include Joubert Syndrome 36 and Orofaciodigital Syndrome Vi. An important paralog of this gene is FAM149A. Involved in the localization of proteins to the cilium and cilium assembly. Indirectly regulates the signaling functions of the cilium, being required for normal SHH/smoothened signaling and proper development.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.