Thermo Fisher Scientific AQR Polyclonal Antibody
인간 AQR 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 제공되며 PBS 버퍼에 40% 글리세롤 포함. 연구용 전용 제품.
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Thermo Fisher Scientific AQR Polyclonal Antibody
Applications
- Immunocytochemistry (ICC/IF)
Tested Dilution: 0.25–2 µg/mL
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human AQR (Product #RP-106653) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662156 |
Product Specific Information
Immunogen sequence:
DEWEGLRKHDV CFLITVRPTK PYGTKFDRRR PFIEQVGLVY VRGCEIQGML DDKGRVIEDG PEPRPNLRGE SRTFRVFLDP NQYQQDMTNT IQNGAEDVYE TFNI
Highest antigen sequence identity to the following orthologs: mouse 98%, rat 98%.
Target Information
Involved in pre-mRNA splicing as a component of the spliceosome (PubMed:11991638, PubMed:25599396, PubMed:28502770, PubMed:28076346).
Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP biogenesis (PubMed:16949364).
Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly (PubMed:16949364).
May act by helping the folding of the snoRNA sequence.
Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing (PubMed:16949364).
Has ATP-dependent RNA helicase activity and can unwind double-stranded RNA molecules with a 3′ overhang (in vitro) (PubMed:25599396).
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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