Thermo Fisher Scientific DDIT3 Monoclonal Antibody (OTI2D3), TrueMAB
인간 DDIT3(CHOP) 단백질을 인식하는 Mouse IgG2a 단클론 항체로, WB 및 IHC(P) 실험에 적합합니다. 고순도 친화 크로마토그래피 정제 제품이며, PBS/BSA/glycerol buffer에 보존됩니다. 연구용으로 ER 스트레스 관련 단백질 분석에 활용됩니다.
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Thermo Fisher Scientific DDIT3 Monoclonal Antibody (OTI2D3), TrueMAB
Applications and Tested Dilution
- Western Blot (WB): 1:500
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D3 |
| Immunogen | Full length human recombinant protein of human DDIT3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
GADD153 (also known as DDIT3 or CHOP) is a small nuclear protein that dimerizes with transcription factors C/EBPα and C/EBPβ. The dimer inhibits normal C/EBP binding and function, while gaining activity toward non-classical stress-related targets. Under normal conditions, GADD153 is not expressed at detectable levels but is highly upregulated during cellular or ER stress, such as treatment with tunicamycin, nutrient starvation, or reducing agents affecting calcium flux across the ER membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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