Thermo Fisher Scientific MLL4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1370-1570 of human KMT2B (NP_0555421) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MLL4,uniProtId:Q9UMN6-1,ncbiNodeId:9606,antigenRange:1370-1570,antigenLength:2715,antigenImageFileName:PA5-116906_MLL4_Q9UMN6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-116906_MLL4_Q9UMN6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.81 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2901536

Product Specific Information

Positive Samples: THP-1, Mouse testis, Mouse brain

Immunogen sequence: GLSDEDYEIL SGLPDSVLYT CGPCAGAAQP RWREALSGAL QGGLRQVLQG LLSSKVVGPL LLCTQCGPDG KQLHPGPCGL QAVSQRFEDG HYKSVHSFME DMVGILMRHS EEGETPDRRA GGQMKGLLLK LLESAFGWFD AHDPKYWRRS TRLPNGVLPN AVLPPSLDHV YAQWRQQEPE TPESGQPPGD PSAAFQGKDP A

Target Information

This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.