Thermo Fisher Scientific PF4 Polyclonal Antibody, MaxPab
PF4 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot에 적합합니다. 인간 단백질에 반응하며, 액상 형태로 제공됩니다. PBS(pH 7.4)에 보존되며, -20°C에서 보관해야 합니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- H00005196-D01P
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | PF4 (NP_002610.1, 1 a.a. ~ 101 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MSSAAGFCAS RPGLLFLGLL LLPLVVAFAS AEAEEDGDLQ CLCVKTTSQV RPRHITSLEV IKAGPHCPTA QLIATLKNGR KICLDLQAPL YKKIIKKLLE S
Target Information
Platelet factor-4 (PF4) is a 70-amino acid protein released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its main physiological role is to neutralize heparin-like molecules on the endothelial surface of blood vessels, inhibiting local antithrombin III activity and promoting coagulation. PF4 also acts as a chemoattractant for neutrophils and fibroblasts, suggesting a role in inflammation and wound repair (Eisman et al., 1990).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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