Thermo Fisher Scientific HMGA1 Polyclonal Antibody
HMGA1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, ICC/IF, Flow Cytometry에 사용 가능. 인간에 반응하며, 서열 상 햄스터, 마우스, 랫과도 반응 예측. 액상 형태로 2 mg/mL 농도, PBS buffer에 0.09% sodium azide 포함. 연구용 한정.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:10–1:50 |
| Flow Cytometry (Flow) | 1:10–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 64–93 amino acids from the C-terminal region of human HMGA1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Size-exclusion - Dialysis, Ammonium sulfate precipitation |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2543615 |
Product Specific Information
This antibody is predicted to react with hamster, mouse, and rat based on sequence homology.
Target Information
HMGA1 encodes a non-histone protein involved in multiple cellular processes, including regulation of inducible gene transcription, retroviral integration into chromosomes, and metastatic progression of cancer cells. The protein binds preferentially to the minor groove of A+T-rich DNA regions and exhibits conformational flexibility upon substrate binding. It is frequently acetylated and localized in the nucleus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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