Thermo Fisher Scientific ADAMTS2 Polyclonal Antibody
인간 ADAMTS2 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 고순도 친화 크로마토그래피 정제, PBS 기반 용액 형태로 제공되며 -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5103581
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ADAMTS2 (Accession O95450), corresponding to amino acid residues F570–A620 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852917 |
Product Specific Information
Antibody detects endogenous levels of total ADAMTS2.
Target Information
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene excises the N-propeptide of type I, type II, and type V procollagens. Mutations cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in two transcript variants, with the short transcript encoding a protein lacking significant procollagen N-peptidase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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