Thermo Fisher Scientific TMEM2 Polyclonal Antibody
TMEM2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 인간·마우스·랫트 반응성을 갖습니다. 세포막 히알루로니다아제 연구에 활용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within Human Transmembrane protein 2 (aa 98–147/1,383) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932608 |
Target Information
This gene encodes a type II transmembrane protein belonging to the interferon-induced transmembrane (IFITM) protein superfamily.
The encoded protein acts as a cell surface hyaluronidase, cleaving extracellular high molecular weight hyaluronan into intermediate size fragments before internalization and lysosomal degradation.
It also exhibits interferon-mediated antiviral activity through activation of the JAK-STAT signaling pathway.
Activation by transcription factor SOX4 in breast cancer cells mediates pathological effects on cancer progression.
Mutations in this gene are associated with autosomal recessive non-syndromic hearing loss.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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