Thermo Fisher Scientific Cdc37 Recombinant Rabbit Monoclonal Antibody (23GB3440)
Cdc37 단백질을 인식하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체입니다. Western blot, ICC/IF, Flow cytometry에 적합하며, 높은 특이성과 재현성을 제공합니다. HEK293F 발현 시스템에서 생산되며, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunocytochemistry (ICC/IF) | 1:1,000 |
| Flow Cytometry (Flow) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB3440 |
| Immunogen | A synthetic peptide of human Cdc37 (2–30AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
In S. cerevisiae, Cdc37 is an important regulator of the cell division cycle through its action on cyclin-dependent kinases (CDKs). It is also associated with signaling pathways and kinases unrelated to cell cycle control, including v-Src, casein kinase II, MPS1 kinase, and the sevenless receptor tyrosine kinase.
Cdc37 interacts with HSP90 and shares many cellular targets. It was previously described as p50, found complexed with Src-family kinases (Fyn, Yes, Fes, Lck, Fgr), Raf, and pp60v-src.
Cdc37 functions as a chaperone independently and in concert with HSP90, and is necessary for HSP90 binding to Cdk4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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