Thermo Fisher Scientific DYNC1H1 Polyclonal Antibody
DYNC1H1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 사용 가능. Human, Mouse, Rat 반응성. Affinity chromatography로 정제된 액상 항체이며 -20°C 보관. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DYNC1H1 (Accession Q14204), corresponding to amino acid residues S2082–P2132 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899785 |
Product Specific Information
This antibody detects endogenous levels of total DYNC1H1.
Target Information
ZEB2, initially identified as Smad interacting-protein 1, is a nuclear DNA-binding transcriptional repressor that interacts with activated SMADs. Similar to ZEB1, it inhibits transcription of the E-cadherin gene and induces epithelial-mesenchymal transition, a process controlling cell migration during embryonic development and wound healing.
ZEB2 can protect cells from DNA damage-induced apoptosis, potentially contributing to tumor progression. It is often observed in the cytoplasm of various cancer tissues, suggesting localization regulation in normal and tumor cells. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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