Thermo Fisher Scientific ERK3 Monoclonal Antibody (OTI5E1), TrueMAB
ERK3 단백질을 인식하는 Mouse Monoclonal Antibody. Western blot과 Immunocytochemistry에 적합. Human 시료에 반응하며, 액상 형태로 제공. Affinity chromatography로 정제되어 높은 특이성 보유. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5E1 |
| Immunogen | Recombinant protein expressed in E. coli corresponding to amino acids 345–721 of human ERK3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene belongs to the Ser/Thr protein kinase family and is closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases, also known as extracellular signal-regulated kinases (ERKs), are activated through phosphorylation cascades and serve as integration points for multiple biochemical signals.
This kinase is localized in the nucleus and is activated in fibroblasts upon treatment with serum or phorbol esters.
Tissue specificity: Highest expression in skeletal muscle, followed by brain. Also expressed in heart, placenta, lung, liver, pancreas, kidney, and skin fibroblasts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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