
Thermo Fisher Scientific Desmoglein-1 (DSG1) Monoclonal Antibody (18D4)
Desmoglein-1 단백질을 표적하는 Mouse IgG1 단클론 항체로, WB, ICC/IF, Flow Cytometry에 적합합니다. Human 시료 반응성이 있으며, Protein A/G 정제, PBS 용액 형태로 제공됩니다. 연구용 전용 시약입니다.
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Thermo Fisher Scientific Desmoglein-1 (DSG1) Monoclonal Antibody (18D4)
Applications & Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 18D4 |
| Immunogen | Human desmoglein-1 intracellular domain |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Three desmoglein subfamily members have been identified, all belonging to the cadherin cell adhesion molecule superfamily. The desmoglein gene family is clustered on chromosome 18. Desmoglein-1 has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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