Thermo Fisher Scientific MSI2 Polyclonal Antibody, MaxPab

Applications

• Western Blot (WB): Tested dilution 1:1,000

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MEANGSQGTS GSANDSQHDP GKMFIGGLSW QTSPDSLRDY FSKFGEIREC MVMRDPTTKR SRGFGFVTFA DPASVDKVLG QPHHELDSKT IDPKVAFPRR AQPKMVTRTK KIFVGGLSAN TVVEDVKQYF EQFGKVEDAM LMFDKTTNRH RGFGFVTFEN EDVVEKVCEI HFHEINNKMV ECKKAQPKEV MFPPGTRGRA RGLPYTMDAF MLGMGMLGYP NFVATYGRGY PGFAPSYGYQ FPGFPAAAYG PVAAAAVAAA RGSGSNPARP GGFPGANSPG PVADLYGPAS QDSGVGNYIS AASPQPGSGF GHGIAGPLIA TAFTNGYH

Target Information

Msi2 (musashi homolog 2), also known as MSI2H, is a 328 amino acid protein localized in the cytoplasm and contains two RRM (RNA recognition motif) domains. It is ubiquitously expressed at low levels and functions as an RNA-binding protein that regulates target mRNA expression, contributing to stem cell proliferation and maintenance in the central nervous system. Msi2 is phosphorylated posttranslationally and upregulated after brain injury, suggesting roles in healing and regeneration. Chromosomal aberrations involving Msi2 are linked to chronic myeloid leukemia progression. Multiple isoforms exist due to alternative splicing.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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